Stochastic Processes in Evolution, Ecology and Genetics Processus stochastiques en évolution, écologie et génétique (Org:

نویسنده

  • Don Dawson
چکیده

Kingman’s coalescent is a process which describes how ancestral lineages merge when one goes backward in time into the past. Since its introduction in the 80’s, it has become the standard genealogy model in population genetics. One of the main question in this field is to try to detect the trace of natural selection’s action in today’s genomes. One of the main tool for doing so is the celebrated Ewens sampling formula which describes the expected genetic diversity in a neutral, constant-size population (for which Kingman’s coalescent accurately describes the genealogy). As such, it gives the nil hypothesis for statistical tests designed to detect selection.

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تاریخ انتشار 2008